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Application of the random forest algorithm to Streptococcus pyogenes response regulator allele variation: from machine learning to evolutionary models

Group A Streptococcus (GAS) is a globally significant bacterial pathogen. The GAS genotyping gold standard characterises the nucleotide variation of emm, which encodes a surface-exposed protein that is recombinogenic and under immune-based selection pressure. Within a supervised learning methodology...

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Detalles Bibliográficos
Autores principales: Buckley, Sean J., Harvey, Robert J., Shan, Zack
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8209152/
https://www.ncbi.nlm.nih.gov/pubmed/34135390
http://dx.doi.org/10.1038/s41598-021-91941-6