Machine learning algorithm improved automated droplet classification of ddPCR for detection of BRAF V600E in paraffin-embedded samples

Somatic mutations in cancer driver genes can help diagnosis, prognosis and treatment decisions. Formalin-fixed paraffin-embedded (FFPE) specimen is the main source of DNA for somatic mutation detection. To overcome constraints of DNA isolated from FFPE, we compared pyrosequencing and ddPCR analysis...

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Detalles Bibliográficos
Autores principales: Colozza-Gama, Gabriel A., Callegari, Fabiano, Bešič, Nikola, Paniza, Ana Carolina de J., Cerutti, Janete M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8209227/
https://www.ncbi.nlm.nih.gov/pubmed/34135377
http://dx.doi.org/10.1038/s41598-021-92014-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8209227/
https://www.ncbi.nlm.nih.gov/pubmed/34135377
http://dx.doi.org/10.1038/s41598-021-92014-4

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