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Protein residue network analysis reveals fundamental properties of the human coagulation factor VIII
Hemophilia A is an X-linked inherited blood coagulation disorder caused by the production and circulation of defective coagulation factor VIII protein. People living with this condition receive either prophylaxis or on-demand treatment, and approximately 30% of patients develop inhibitor antibodies,...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8209229/ https://www.ncbi.nlm.nih.gov/pubmed/34135429 http://dx.doi.org/10.1038/s41598-021-92201-3 |