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Protein residue network analysis reveals fundamental properties of the human coagulation factor VIII

Hemophilia A is an X-linked inherited blood coagulation disorder caused by the production and circulation of defective coagulation factor VIII protein. People living with this condition receive either prophylaxis or on-demand treatment, and approximately 30% of patients develop inhibitor antibodies,...

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Detalles Bibliográficos
Autores principales:	Lopes, Tiago J. S., Rios, Ricardo, Nogueira, Tatiane, Mello, Rodrigo F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8209229/ https://www.ncbi.nlm.nih.gov/pubmed/34135429 http://dx.doi.org/10.1038/s41598-021-92201-3

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