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Suv4-20h2 protects against influenza virus infection by suppression of chromatin loop formation

The spatial organization of chromatin is known to be highly dynamic in response to environmental stress. However, it remains unknown how chromatin dynamics contributes to or modulates disease pathogenesis. Here, we show that upon influenza virus infection, the H4K20me3 methyltransferase Suv4-20h2 bi...

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Detalles Bibliográficos
Autores principales: Shiimori, Masami, Ichida, Yu, Nukiwa, Ryota, Sakuma, Toshie, Abe, Haruka, Kajitani, Rei, Fujino, Yuji, Kikuchi, Akira, Kawamura, Takeshi, Kodama, Tatsuhiko, Toyooka, Shinichi, Shirahige, Katsuhiko, Schotta, Gunnar, Kuba, Keiji, Itoh, Takehiko, Imai, Yumiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8209278/
https://www.ncbi.nlm.nih.gov/pubmed/34169237
http://dx.doi.org/10.1016/j.isci.2021.102660