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Suv4-20h2 protects against influenza virus infection by suppression of chromatin loop formation
The spatial organization of chromatin is known to be highly dynamic in response to environmental stress. However, it remains unknown how chromatin dynamics contributes to or modulates disease pathogenesis. Here, we show that upon influenza virus infection, the H4K20me3 methyltransferase Suv4-20h2 bi...
Autores principales: | Shiimori, Masami, Ichida, Yu, Nukiwa, Ryota, Sakuma, Toshie, Abe, Haruka, Kajitani, Rei, Fujino, Yuji, Kikuchi, Akira, Kawamura, Takeshi, Kodama, Tatsuhiko, Toyooka, Shinichi, Shirahige, Katsuhiko, Schotta, Gunnar, Kuba, Keiji, Itoh, Takehiko, Imai, Yumiko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8209278/ https://www.ncbi.nlm.nih.gov/pubmed/34169237 http://dx.doi.org/10.1016/j.isci.2021.102660 |
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