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In vivo coupling of dendritic complexity with presynaptic density in primary tauopathies

Understanding the cellular underpinnings of neurodegeneration remains a challenge; loss of synapses and dendritic arborization are characteristic and can be quantified in vivo, with [(11)C]UCB-J PET and MRI-based Orientation Dispersion Imaging (ODI), respectively. We aimed to assess how both measure...

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Detalles Bibliográficos
Autores principales: Mak, Elijah, Holland, Negin, Jones, P. Simon, Savulich, George, Low, Audrey, Malpetti, Maura, Kaalund, Sanne S, Passamonti, Luca, Rittman, Timothy, Romero-Garcia, Rafael, Manavaki, Roido, Williams, Guy B., Hong, Young T., Fryer, Tim D., Aigbirhio, Franklin I., O'Brien, John T, Rowe, James B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8209289/
https://www.ncbi.nlm.nih.gov/pubmed/33631470
http://dx.doi.org/10.1016/j.neurobiolaging.2021.01.016