Striatal Synapse Degeneration and Dysfunction Are Reversed by Reactivation of Wnt Signaling

Synapse degeneration in the striatum has been associated with the early stages of Parkinson’s and Huntington’s diseases (PD and HD). However, the molecular mechanisms that trigger synaptic dysfunction and loss are not fully understood. Increasing evidence suggests that deficiency in Wnt signaling tr...

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Detalles Bibliográficos
Autores principales: Galli, Soledad, Stancheva, Stefka H., Dufor, Tom, Gibb, Alasdair J., Salinas, Patricia C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8209303/
https://www.ncbi.nlm.nih.gov/pubmed/34149390
http://dx.doi.org/10.3389/fnsyn.2021.670467

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8209303/
https://www.ncbi.nlm.nih.gov/pubmed/34149390
http://dx.doi.org/10.3389/fnsyn.2021.670467

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