Suppression of Microgliosis With the Colony-Stimulating Factor 1 Receptor Inhibitor PLX3397 Does Not Attenuate Memory Defects During Epileptogenesis in the Rat

Events of status epilepticus (SE) trigger the development of temporal lobe epilepsy (TLE), a type of focal epilepsy that is commonly drug-resistant and is highly comorbid with cognitive deficits. While SE-induced hippocampal injury, accompanied by gliosis and neuronal loss, typically disrupts cognit...

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Detalles Bibliográficos
Autores principales: Wyatt-Johnson, Season K., Sommer, Alexandra L., Shim, Kevin Y., Brewster, Amy L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Neurology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8209304/
https://www.ncbi.nlm.nih.gov/pubmed/34149593
http://dx.doi.org/10.3389/fneur.2021.651096

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8209304/
https://www.ncbi.nlm.nih.gov/pubmed/34149593
http://dx.doi.org/10.3389/fneur.2021.651096

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