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An eIF3a gene mutation dysregulates myocardium growth with left ventricular noncompaction via the p-ERK1/2 pathway

Left ventricular noncompaction (LVNC) is a heterogeneous disorder with unclear genetic causes and an unknown mechanism. eIF3a, an important member of the Eukaryotic translation initiation factor 3 (eIF3) family, is involved in multiple biological processes, including cell proliferation and migration...

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Detalles Bibliográficos
Autores principales: Ge, Mei, Bai, Xuehan, Liu, Aoyi, Liu, Lingjuan, Tian, Jie, Lu, Tiewei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chongqing Medical University 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8209309/
https://www.ncbi.nlm.nih.gov/pubmed/34179316
http://dx.doi.org/10.1016/j.gendis.2020.02.003