Generation and Characterization of Mouse Models of C3 Glomerulonephritis With CFI D288G and P467S Mutations

C3 glomerulopathy (C3GP) is a disease entity caused by abnormality of the complement alternative pathway (AP) and characterized by C3 deposition in glomeruli. Many variations or mutations of complement factors are believed to underlie the susceptibility to C3GP, but there is a lack of experimental e...

Descripción completa

Detalles Bibliográficos
Autores principales: Song, Hui, Zhang, Mingchao, Li, Xue, Xu, Feng, Zhang, Difei, Zhu, Xiaodong, Zhang, Jiong, Qin, Weisong, Shi, Shaolin, Wen, Jiqiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8209374/
https://www.ncbi.nlm.nih.gov/pubmed/34149444
http://dx.doi.org/10.3389/fphys.2021.649801

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8209374/
https://www.ncbi.nlm.nih.gov/pubmed/34149444
http://dx.doi.org/10.3389/fphys.2021.649801

Ejemplares similares