Research informatics and the COVID-19 pandemic: Challenges, innovations, lessons learned, and recommendations

The recipients of NIH’s Clinical and Translational Science Awards (CTSA) have worked for over a decade to build informatics infrastructure in support of clinical and translational research. This infrastructure has proved invaluable for supporting responses to the current COVID-19 pandemic through di...

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Autores principales: Bookman, Richard J., Cimino, James J., Harle, Christopher A., Kost, Rhonda G., Mooney, Sean, Pfaff, Emily, Rojevsky, Svetlana, Tobin, Jonathan N., Wilcox, Adam, Tsinoremas, Nick F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8209435/
https://www.ncbi.nlm.nih.gov/pubmed/34192063
http://dx.doi.org/10.1017/cts.2021.26
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author Bookman, Richard J.
Cimino, James J.
Harle, Christopher A.
Kost, Rhonda G.
Mooney, Sean
Pfaff, Emily
Rojevsky, Svetlana
Tobin, Jonathan N.
Wilcox, Adam
Tsinoremas, Nick F.
author_facet Bookman, Richard J.
Cimino, James J.
Harle, Christopher A.
Kost, Rhonda G.
Mooney, Sean
Pfaff, Emily
Rojevsky, Svetlana
Tobin, Jonathan N.
Wilcox, Adam
Tsinoremas, Nick F.
author_sort Bookman, Richard J.
collection PubMed
description The recipients of NIH’s Clinical and Translational Science Awards (CTSA) have worked for over a decade to build informatics infrastructure in support of clinical and translational research. This infrastructure has proved invaluable for supporting responses to the current COVID-19 pandemic through direct patient care, clinical decision support, training researchers and practitioners, as well as public health surveillance and clinical research to levels that could not have been accomplished without the years of ground-laying work by the CTSAs. In this paper, we provide a perspective on our COVID-19 work and present relevant results of a survey of CTSA sites to broaden our understanding of the key features of their informatics programs, the informatics-related challenges they have experienced under COVID-19, and some of the innovations and solutions they developed in response to the pandemic. Responses demonstrated increased reliance by healthcare providers and researchers on access to electronic health record (EHR) data, both for local needs and for sharing with other institutions and national consortia. The initial work of the CTSAs on data capture, standards, interchange, and sharing policies all contributed to solutions, best illustrated by the creation, in record time, of a national clinical data repository in the National COVID-19 Cohort Collaborative (N3C). The survey data support seven recommendations for areas of informatics and public health investment and further study to support clinical and translational research in the post-COVID-19 era.
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spelling pubmed-82094352021-06-17 Research informatics and the COVID-19 pandemic: Challenges, innovations, lessons learned, and recommendations Bookman, Richard J. Cimino, James J. Harle, Christopher A. Kost, Rhonda G. Mooney, Sean Pfaff, Emily Rojevsky, Svetlana Tobin, Jonathan N. Wilcox, Adam Tsinoremas, Nick F. J Clin Transl Sci Special Communications The recipients of NIH’s Clinical and Translational Science Awards (CTSA) have worked for over a decade to build informatics infrastructure in support of clinical and translational research. This infrastructure has proved invaluable for supporting responses to the current COVID-19 pandemic through direct patient care, clinical decision support, training researchers and practitioners, as well as public health surveillance and clinical research to levels that could not have been accomplished without the years of ground-laying work by the CTSAs. In this paper, we provide a perspective on our COVID-19 work and present relevant results of a survey of CTSA sites to broaden our understanding of the key features of their informatics programs, the informatics-related challenges they have experienced under COVID-19, and some of the innovations and solutions they developed in response to the pandemic. Responses demonstrated increased reliance by healthcare providers and researchers on access to electronic health record (EHR) data, both for local needs and for sharing with other institutions and national consortia. The initial work of the CTSAs on data capture, standards, interchange, and sharing policies all contributed to solutions, best illustrated by the creation, in record time, of a national clinical data repository in the National COVID-19 Cohort Collaborative (N3C). The survey data support seven recommendations for areas of informatics and public health investment and further study to support clinical and translational research in the post-COVID-19 era. Cambridge University Press 2021-03-16 /pmc/articles/PMC8209435/ /pubmed/34192063 http://dx.doi.org/10.1017/cts.2021.26 Text en © The Association for Clinical and Translational Science 2021 https://creativecommons.org/licenses/by/4.0/This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Special Communications
Bookman, Richard J.
Cimino, James J.
Harle, Christopher A.
Kost, Rhonda G.
Mooney, Sean
Pfaff, Emily
Rojevsky, Svetlana
Tobin, Jonathan N.
Wilcox, Adam
Tsinoremas, Nick F.
Research informatics and the COVID-19 pandemic: Challenges, innovations, lessons learned, and recommendations
title Research informatics and the COVID-19 pandemic: Challenges, innovations, lessons learned, and recommendations
title_full Research informatics and the COVID-19 pandemic: Challenges, innovations, lessons learned, and recommendations
title_fullStr Research informatics and the COVID-19 pandemic: Challenges, innovations, lessons learned, and recommendations
title_full_unstemmed Research informatics and the COVID-19 pandemic: Challenges, innovations, lessons learned, and recommendations
title_short Research informatics and the COVID-19 pandemic: Challenges, innovations, lessons learned, and recommendations
title_sort research informatics and the covid-19 pandemic: challenges, innovations, lessons learned, and recommendations
topic Special Communications
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8209435/
https://www.ncbi.nlm.nih.gov/pubmed/34192063
http://dx.doi.org/10.1017/cts.2021.26
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