TNF-mediated alveolar macrophage necroptosis drives disease pathogenesis during respiratory syncytial virus infection

Respiratory syncytial virus (RSV) is the major cause of acute bronchiolitis in infants under 2 years old. Necroptosis has been implicated in the outcomes of respiratory virus infections. We report that RSV infection triggers necroptosis in primary mouse macrophages and human monocytes in a RIPK1-, R...

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Detalles Bibliográficos
Autores principales: Santos, Leonardo Duarte, Antunes, Krist Helen, Muraro, Stéfanie Primon, de Souza, Gabriela Fabiano, da Silva, Amanda Gonzalez, Felipe, Jaqueline de Souza, Zanetti, Larissa Cardoso, Czepielewski, Rafael Sanguinetti, Magnus, Karen, Scotta, Marcelo, Mattiello, Rita, Maito, Fabio, de Souza, Ana Paula Duarte, Weinlich, Ricardo, Vinolo, Marco Aurélio Ramirez, Porto, Bárbara Nery
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Respiratory Society 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8209485/
https://www.ncbi.nlm.nih.gov/pubmed/33303545
http://dx.doi.org/10.1183/13993003.03764-2020

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8209485/
https://www.ncbi.nlm.nih.gov/pubmed/33303545
http://dx.doi.org/10.1183/13993003.03764-2020

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