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Promotion of Bone Lesions Through the Myeloma Integrin α6-Mediated Osteolytic Signaling
Osteolytic destruction is a hallmark of multiple myeloma and impairs myeloma patients’ quality of life. However, the molecular mechanism underlying the pathogenesis of myeloma-associated bone disease remains unclear. In this study, we demonstrate the role of myeloma cell-expressed integrin α6 in bon...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8209508/ https://www.ncbi.nlm.nih.gov/pubmed/34150666 http://dx.doi.org/10.3389/fonc.2021.692190 |