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CSE1L promotes nuclear accumulation of transcriptional coactivator TAZ and enhances invasiveness of human cancer cells

The transcriptional coactivator with PDZ-binding motif (TAZ) (WWTR1) induces epithelial–mesenchymal transition and enhances drug resistance in multiple cancers. TAZ has been shown to interact with transcription factors in the nucleus, but when phosphorylated, translocates to the cytoplasm and is deg...

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Detalles Bibliográficos
Autores principales: Nagashima, Shunta, Maruyama, Junichi, Honda, Kaori, Kondoh, Yasumitsu, Osada, Hiroyuki, Nawa, Makiko, Nakahama, Ken-ichi, Ishigami-Yuasa, Mari, Kagechika, Hiroyuki, Sugimura, Haruhiko, Iwasa, Hiroaki, Arimoto-Matsuzaki, Kyoko, Nishina, Hiroshi, Hata, Yutaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8209642/
https://www.ncbi.nlm.nih.gov/pubmed/34022224
http://dx.doi.org/10.1016/j.jbc.2021.100803