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Protocol to establish a lung adenocarcinoma immunotherapy allograft mouse model with FACS and immunofluorescence-based analysis of tumor response

Anti-PD-1/PD-L1 therapy shows long-term effects in many cancer types, but resistance and relapse remain the main limitations of this therapy. Here, we describe a protocol to evaluate the tumor response to immunotherapy in a mouse lung cancer model. The protocol includes the establishment of the lung...

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Detalles Bibliográficos
Autores principales: Peng, Zhengxin, Yu, Man, Lin, Jiaming, Dong, Tianqi, Zhang, Xiao, Shi, Mingjun, Qin, Min, Li, Shasha, Guo, Wencong, Zhang, Huixia, Sun, Shuguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8209678/
https://www.ncbi.nlm.nih.gov/pubmed/34169289
http://dx.doi.org/10.1016/j.xpro.2021.100595