Structural basis for aggregate dissolution and refolding by the Mycobacterium tuberculosis ClpB-DnaK bi-chaperone system

The M. tuberculosis (Mtb) ClpB is a protein disaggregase that helps to rejuvenate the bacterial cell. DnaK is a protein foldase that can function alone, but it can also bind to the ClpB hexamer to physically couple protein disaggregation with protein refolding, although the molecular mechanism is no...

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Detalles Bibliográficos
Autores principales: Yin, Yanting, Feng, Xiang, Yu, Hongjun, Fay, Allison, Kovach, Amanda, Glickman, Michael S., Li, Huilin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8209680/
https://www.ncbi.nlm.nih.gov/pubmed/34038719
http://dx.doi.org/10.1016/j.celrep.2021.109166

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8209680/
https://www.ncbi.nlm.nih.gov/pubmed/34038719
http://dx.doi.org/10.1016/j.celrep.2021.109166

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