Cas9-targeted nanopore sequencing reveals epigenetic heterogeneity after de novo assembly of native full-length hepatitis B virus genomes

Hepatitis B virus (HBV) contains a 3.2 kb DNA genome and causes acute and chronic hepatitis. HBV infection is a global health problem, with 350 million chronically infected people at increased risk of developing liver disease and hepatocellular carcinoma (HCC). Methylation of HBV DNA in a CpG contex...

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Detalles Bibliográficos
Autores principales: Goldsmith, Chloe, Cohen, Damien, Dubois, Anaëlle, Martinez, Maria Guadalupe, Petitjean, Kilian, Corlu, Anne, Testoni, Barbara, Hernandez-Vargas, Hector, Chemin, Isabelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Microbiology Society 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8209722/
https://www.ncbi.nlm.nih.gov/pubmed/34003741
http://dx.doi.org/10.1099/mgen.0.000507

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8209722/
https://www.ncbi.nlm.nih.gov/pubmed/34003741
http://dx.doi.org/10.1099/mgen.0.000507

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