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The Isotopic Ac-IP Tag Enables Multiplexed Proteome Quantification in Data-Independent Acquisition Mode

[Image: see text] Data-independent acquisition (DIA) is an increasingly used approach for quantitative proteomics. However, most current isotope labeling strategies are not suitable for DIA as they lead to more complex MS2 spectra or severe ratio distortion. As a result, DIA suffers from a lower thr...

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Detalles Bibliográficos
Autores principales: Tian, Xiaobo, de Vries, Marcel P., Permentier, Hjalmar P., Bischoff, Rainer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8209779/
https://www.ncbi.nlm.nih.gov/pubmed/34053216
http://dx.doi.org/10.1021/acs.analchem.1c00453