SARS‐CoV‐2 sensing by RIG‐I and MDA5 links epithelial infection to macrophage inflammation

SARS‐CoV‐2 infection causes broad‐spectrum immunopathological disease, exacerbated by inflammatory co‐morbidities. A better understanding of mechanisms underpinning virus‐associated inflammation is required to develop effective therapeutics. Here, we discover that SARS‐CoV‐2 replicates rapidly in lu...

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Detalles Bibliográficos
Autores principales: Thorne, Lucy G, Reuschl, Ann‐Kathrin, Zuliani‐Alvarez, Lorena, Whelan, Matthew V X, Turner, Jane, Noursadeghi, Mahdad, Jolly, Clare, Towers, Greg J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8209947/
https://www.ncbi.nlm.nih.gov/pubmed/34101213
http://dx.doi.org/10.15252/embj.2021107826

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8209947/
https://www.ncbi.nlm.nih.gov/pubmed/34101213
http://dx.doi.org/10.15252/embj.2021107826

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