Homologous recombination, cancer and the ‘RAD51 paradox’

Genetic instability is a hallmark of cancer cells. Homologous recombination (HR) plays key roles in genome stability and variability due to its roles in DNA double-strand break and interstrand crosslink repair, and in the protection and resumption of arrested replication forks. HR deficiency leads t...

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Detalles Bibliográficos
Autores principales: Matos-Rodrigues, Gabriel, Guirouilh-Barbat, Josée, Martini, Emmanuelle, Lopez, Bernard S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Short Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8209977/
https://www.ncbi.nlm.nih.gov/pubmed/34316706
http://dx.doi.org/10.1093/narcan/zcab016

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8209977/
https://www.ncbi.nlm.nih.gov/pubmed/34316706
http://dx.doi.org/10.1093/narcan/zcab016

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