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Molecular correlates of immune cytolytic subgroups in colorectal cancer by integrated genomics analysis

Although immune checkpoint inhibition (ICI) has shown promising results in metastatic dMMR/MSI-H colorectal cancer (CRC), the majority of pMMR/MSS patients do not respond to such therapies. To systematically evaluate the determinants of immune response in CRC, we explored whether patients with diver...

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Detalles Bibliográficos
Autores principales: Roufas, Constantinos, Georgakopoulos-Soares, Ilias, Zaravinos, Apostolos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8210146/
https://www.ncbi.nlm.nih.gov/pubmed/34316699
http://dx.doi.org/10.1093/narcan/zcab005