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Characterization of the MurT/GatD complex in Mycobacterium tuberculosis towards validating a novel anti-tubercular drug target

OBJECTIVES: Identification and validation of novel therapeutic targets is imperative to tackle the rise of drug resistance in tuberculosis. An essential Mur ligase-like gene (Rv3712), expected to be involved in cell-wall peptidoglycan (PG) biogenesis and conserved across mycobacteria, including the...

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Detalles Bibliográficos
Autores principales: Maitra, Arundhati, Nukala, Syamasundari, Dickman, Rachael, Martin, Liam T, Munshi, Tulika, Gupta, Antima, Shepherd, Adrian J, Arnvig, Kristine B, Tabor, Alethea B, Keep, Nicholas H, Bhakta, Sanjib
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8210147/
https://www.ncbi.nlm.nih.gov/pubmed/34223102
http://dx.doi.org/10.1093/jacamr/dlab028