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Pharmacological inhibition of EZH2 by GSK126 decreases atherosclerosis by modulating foam cell formation and monocyte adhesion in apolipoprotein E-deficient mice

Histone modifications play an important role in the occurrence and development of atherosclerosis in human and atherosclerosis-prone mice. Histone methylation in macrophages, monocytes and endothelial cells markedly influence the progression of atherosclerosis. However, it remains unclear whether tr...

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Detalles Bibliográficos
Autores principales: Wei, Xianjing, Zhang, Ying, Xie, Lianna, Wang, Kaijun, Wang, Xiaoqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8210282/
https://www.ncbi.nlm.nih.gov/pubmed/34149887
http://dx.doi.org/10.3892/etm.2021.10273