Cargando…
Pharmacological inhibition of EZH2 by GSK126 decreases atherosclerosis by modulating foam cell formation and monocyte adhesion in apolipoprotein E-deficient mice
Histone modifications play an important role in the occurrence and development of atherosclerosis in human and atherosclerosis-prone mice. Histone methylation in macrophages, monocytes and endothelial cells markedly influence the progression of atherosclerosis. However, it remains unclear whether tr...
Autores principales: | Wei, Xianjing, Zhang, Ying, Xie, Lianna, Wang, Kaijun, Wang, Xiaoqing |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8210282/ https://www.ncbi.nlm.nih.gov/pubmed/34149887 http://dx.doi.org/10.3892/etm.2021.10273 |
Ejemplares similares
-
Blocking EZH2 methylation transferase activity by GSK126 decreases stem cell-like myeloma cells
por: Zeng, Delong, et al.
Publicado: (2016) -
CLI-095 decreases atherosclerosis by modulating foam cell formation in apolipoprotein E-deficient mice
por: WANG, XIAO-QING, et al.
Publicado: (2016) -
Monocyte and macrophage foam cells in diabetes-accelerated atherosclerosis
por: Cervantes, Jocelyn, et al.
Publicado: (2023) -
Combination Treatment with GSK126 and Pomalidomide Induces B-Cell Differentiation in EZH2 Gain-of-Function Mutant Diffuse Large B-Cell Lymphoma
por: Park, Sungryul, et al.
Publicado: (2020) -
Diosgenin and GSK126 Produce Synergistic Effects on Epithelial–Mesenchymal Transition in Gastric Cancer Cells by Mediating EZH2 via the Rho/ROCK Signaling Pathway
por: Liu, Shanshan, et al.
Publicado: (2020)