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TPR1, a novel rifampicin derivative, demonstrates efficacy alone and in combination with doxycycline against the NIAID Category A priority pathogen Francisella tularensis
BACKGROUND: Francisella tularensis is a highly virulent and contagious Gram-negative intracellular bacterium that causes the disease tularaemia in mammals and is classified as a Category A priority pathogen. METHODS: We utilized a systematic analysis of antibacterial potency, extent of dissemination...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8210291/ https://www.ncbi.nlm.nih.gov/pubmed/34223120 http://dx.doi.org/10.1093/jacamr/dlab058 |