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Inhibitory effects of quercetin and its major metabolite quercetin-3-O-β-D-glucoside on human UDP-glucuronosyltransferase 1A isoforms by liquid chromatography-tandem mass spectrometry

Quercetin is a flavonoid that is widely present in plant-derived food. Quercetin-3-O-β-D-glucoside (Q3GA) is a predominant metabolite of quercetin in animal and human plasma. The inhibitory effects of the UDP-glucuronosyl transferases (UGTs) caused by herbal components may be a key factor for the cl...

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Detalles Bibliográficos
Autores principales: Zhang, Rui, Wei, Ye, Yang, Tingyu, Huang, Xixi, Zhou, Jinping, Yang, Chunxiao, Zhou, Jiani, Liu, Yani, Shi, Shaojun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8210293/
https://www.ncbi.nlm.nih.gov/pubmed/34149888
http://dx.doi.org/10.3892/etm.2021.10274