Doxorubicin induces an alarmin-like TLR4-dependent autocrine/paracrine action of Nucleophosmin in human cardiac mesenchymal progenitor cells

BACKGROUND: Doxorubicin (Dox) is an anti-cancer anthracycline drug that causes double-stranded DNA breaks. It is highly effective against several types of tumours; however, it also has adverse effects on regenerative populations of normal cells, such as human cardiac mesenchymal progenitor cells (hC...

Descripción completa

Detalles Bibliográficos
Autores principales: Beji, Sara, D’Agostino, Marco, Gambini, Elisa, Sileno, Sara, Scopece, Alessandro, Vinci, Maria Cristina, Milano, Giuseppina, Melillo, Guido, Napolitano, Monica, Pompilio, Giulio, Capogrossi, Maurizio C., Avitabile, Daniele, Magenta, Alessandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8210386/
https://www.ncbi.nlm.nih.gov/pubmed/34134693
http://dx.doi.org/10.1186/s12915-021-01058-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8210386/
https://www.ncbi.nlm.nih.gov/pubmed/34134693
http://dx.doi.org/10.1186/s12915-021-01058-5

Ejemplares similares