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Notopterol Attenuates Estrogen Deficiency-Induced Osteoporosis via Repressing RANKL Signaling and Reactive Oxygen Species

Integrity of the skeleton is sustained through the balanced activities of osteoblasts and osteoclasts in bone remodeling unit. The balance can be disrupted by excessive osteoclasts activation commonly seen in osteoporosis. Notopterol (NOT) is a main component of Notopterygium incisum which exerts a...

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Detalles Bibliográficos
Autores principales: Chen, Delong, Wang, Qingqing, Li, Ying, Sun, Ping, Kuek, Vincent, Yuan, Jinbo, Yang, Junzheng, Wen, Longfei, Wang, Haibin, Xu, Jiake, Chen, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8210423/
https://www.ncbi.nlm.nih.gov/pubmed/34149419
http://dx.doi.org/10.3389/fphar.2021.664836