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Why Should Metformin Not Be Given in Advanced Kidney Disease? Potential Leads from Computer Simulations

[Image: see text] Metformin is considered as the go-to drug in the treatment of diabetes. However, it is either prescribed in lower doses or not prescribed at all to patients with kidney problems. To find a potential explanation for this practice, we employed atomistic-level computer simulations to...

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Detalles Bibliográficos
Autores principales: Kokic Males, Visnja, Požar, Martina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8210427/
https://www.ncbi.nlm.nih.gov/pubmed/34151116
http://dx.doi.org/10.1021/acsomega.1c01744