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Dynamic innate immune response determines susceptibility to SARS-CoV-2 infection and early replication kinetics
Initial replication of SARS-CoV-2 in the upper respiratory tract is required to establish infection, and the replication level correlates with the likelihood of viral transmission. Here, we examined the role of host innate immune defenses in restricting early SARS-CoV-2 infection using transcriptomi...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8210587/ https://www.ncbi.nlm.nih.gov/pubmed/34128960 http://dx.doi.org/10.1084/jem.20210583 |