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Dynamic innate immune response determines susceptibility to SARS-CoV-2 infection and early replication kinetics

Initial replication of SARS-CoV-2 in the upper respiratory tract is required to establish infection, and the replication level correlates with the likelihood of viral transmission. Here, we examined the role of host innate immune defenses in restricting early SARS-CoV-2 infection using transcriptomi...

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Detalles Bibliográficos
Autores principales:	Cheemarla, Nagarjuna R., Watkins, Timothy A., Mihaylova, Valia T., Wang, Bao, Zhao, Dejian, Wang, Guilin, Landry, Marie L., Foxman, Ellen F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Rockefeller University Press 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8210587/ https://www.ncbi.nlm.nih.gov/pubmed/34128960 http://dx.doi.org/10.1084/jem.20210583

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