Plasma-derived DNA containing-extracellular vesicles induce STING-mediated proinflammatory responses in dermatomyositis

Objectives: Extracellular vesicles (EVs) are lipid bilayer membrane vesicles that are present in various bodily fluids and have been implicated in autoimmune disease pathogenesis. Type I interferons (IFN), specifically IFN-β, are uniquely elevated in dermatomyositis (DM). The stimulator of interfero...

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Detalles Bibliográficos
Autores principales: Li, Yubin, Bax, Christina, Patel, Jay, Vazquez, Thomas, Ravishankar, Adarsh, Bashir, Muhammad M., Grinnell, Madison, Diaz, DeAnna, Werth, Victoria P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8210592/
https://www.ncbi.nlm.nih.gov/pubmed/34158841
http://dx.doi.org/10.7150/thno.59152

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8210592/
https://www.ncbi.nlm.nih.gov/pubmed/34158841
http://dx.doi.org/10.7150/thno.59152

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