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Plasma-derived DNA containing-extracellular vesicles induce STING-mediated proinflammatory responses in dermatomyositis

Objectives: Extracellular vesicles (EVs) are lipid bilayer membrane vesicles that are present in various bodily fluids and have been implicated in autoimmune disease pathogenesis. Type I interferons (IFN), specifically IFN-β, are uniquely elevated in dermatomyositis (DM). The stimulator of interfero...

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Detalles Bibliográficos
Autores principales:	Li, Yubin, Bax, Christina, Patel, Jay, Vazquez, Thomas, Ravishankar, Adarsh, Bashir, Muhammad M., Grinnell, Madison, Diaz, DeAnna, Werth, Victoria P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ivyspring International Publisher 2021
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8210592/ https://www.ncbi.nlm.nih.gov/pubmed/34158841 http://dx.doi.org/10.7150/thno.59152

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