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R13 preserves motor performance in SOD1(G93A) mice by improving mitochondrial function

Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease characterized by death of motor neurons in the brain and spinal cord. However, so far, there is no effective treatment for ALS. Methods: In this study, R13, a prodrug of 7,8-dihydroxyflavone, selectively activating tyrosi...

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Detalles Bibliográficos
Autores principales: Li, Xiao, Chen, Chongyang, Zhan, Xu, Li, Binyao, Zhang, Zaijun, Li, Shupeng, Xie, Yongmei, Song, Xiangrong, Shen, Yuanyuan, Liu, Jianjun, Liu, Ping, Liu, Gong-Ping, Yang, Xifei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8210609/
https://www.ncbi.nlm.nih.gov/pubmed/34158851
http://dx.doi.org/10.7150/thno.56070