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R13 preserves motor performance in SOD1(G93A) mice by improving mitochondrial function
Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease characterized by death of motor neurons in the brain and spinal cord. However, so far, there is no effective treatment for ALS. Methods: In this study, R13, a prodrug of 7,8-dihydroxyflavone, selectively activating tyrosi...
Autores principales: | Li, Xiao, Chen, Chongyang, Zhan, Xu, Li, Binyao, Zhang, Zaijun, Li, Shupeng, Xie, Yongmei, Song, Xiangrong, Shen, Yuanyuan, Liu, Jianjun, Liu, Ping, Liu, Gong-Ping, Yang, Xifei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8210609/ https://www.ncbi.nlm.nih.gov/pubmed/34158851 http://dx.doi.org/10.7150/thno.56070 |
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