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Inhibition of SENP6 restrains cerebral ischemia-reperfusion injury by regulating Annexin-A1 nuclear translocation-associated neuronal apoptosis

Rationale: Annexin-A1 (ANXA1) has previously been proposed to play a crucial role in neuronal apoptosis during ischemic stroke injury. Our recent study demonstrated that ANXA1 was modified by SUMOylation, and that this modification was greatly weakened after cerebral ischemia, but its effect on neur...

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Detalles Bibliográficos
Autores principales: Xia, Qian, Mao, Meng, Zeng, Zhen, Luo, Zhenzhao, Zhao, Yin, Shi, Jing, Li, Xing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8210613/
https://www.ncbi.nlm.nih.gov/pubmed/34158860
http://dx.doi.org/10.7150/thno.60277