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Adjuvant-free peptide vaccine targeting Clec9a on dendritic cells can induce robust antitumor immune response through Syk/IL-21 axis

Dendritic cells (DCs) can process the antigens of cancer vaccine and thus stimulate the CD8(+) T cells to recognize and kill the tumor cells that express these antigens. However, lack of promising carriers for presenting the antigens to DCs is one of the main barriers to the development of clinicall...

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Detalles Bibliográficos
Autores principales: Gou, Shanshan, Wang, Shuai, Liu, Wenwen, Chen, Guanyu, Zhang, Dongyang, Du, Jiangfeng, Yan, Zhongyi, Wang, Hongfei, Zhai, Wenjie, Sui, Xinghua, Wu, Yahong, Qi, Yuanming, Gao, Yanfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8210616/
https://www.ncbi.nlm.nih.gov/pubmed/34158852
http://dx.doi.org/10.7150/thno.56406