EGFR-targeted intraoperative fluorescence imaging detects high-grade glioma with panitumumab-IRDye800 in a phase 1 clinical trial

Rationale: First-line therapy for high-grade gliomas (HGGs) includes maximal safe surgical resection. The extent of resection predicts overall survival, but current neuroimaging approaches lack tumor specificity. The epidermal growth factor receptor (EGFR) is a highly expressed HGG biomarker. We eva...

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Detalles Bibliográficos
Autores principales: Zhou, Quan, van den Berg, Nynke S., Rosenthal, Eben L., Iv, Michael, Zhang, Michael, Vega Leonel, Johana C. M., Walters, Shannon, Nishio, Naoki, Granucci, Monica, Raymundo, Roan, Yi, Grace, Vogel, Hannes, Cayrol, Romain, Lee, Yu-Jin, Lu, Guolan, Hom, Marisa, Kang, Wenying, Hayden Gephart, Melanie, Recht, Larry, Nagpal, Seema, Thomas, Reena, Patel, Chirag, Grant, Gerald A., Li, Gordon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8210618/
https://www.ncbi.nlm.nih.gov/pubmed/34158840
http://dx.doi.org/10.7150/thno.60582

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8210618/
https://www.ncbi.nlm.nih.gov/pubmed/34158840
http://dx.doi.org/10.7150/thno.60582

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