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Discovery of ammosesters by mining the Streptomyces uncialis DCA2648 genome revealing new insight into ammosamide biosynthesis

The ammosamides (AMMs) are a family of pyrroloquinoline alkaloids that exhibits a wide variety of bioactivities. A biosynthetic gene cluster (BGC) that is highly homologous in both gene content and genetic organization to the amm BGC was identified by mining the Streptomyces uncialis DCA2648 genome,...

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Detalles Bibliográficos
Autores principales: Luo, Jun, Yang, Dong, Hindra, Adhikari, Ajeeth, Dong, Liao-Bin, Ye, Fei, Yan, Xiaohui, Rader, Christoph, Shen, Ben
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8210675/
https://www.ncbi.nlm.nih.gov/pubmed/33982054
http://dx.doi.org/10.1093/jimb/kuab027