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Creutzfeldt–Jakob disease in pregnancy: the use of modified RT-QuIC to determine infectivity in placental tissues

Sporadic Creutzfeldt–Jakob Disease (sCJD) rarely affects women of childbearing age. There is currently no evidence of vertical transmission. Given the biosafety implications of performing Caesarean sections (C-section) in these patients, we used sensitive real-time quaking-induced conversion (RT-QuI...

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Detalles Bibliográficos
Autores principales: Luk, Collin C., Mathiason, Candace K., Orrù, Christina D., Jansen, Gerard H., Thiele, Allison, Caughey, Byron, Sim, Valerie L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8210859/
https://www.ncbi.nlm.nih.gov/pubmed/34132175
http://dx.doi.org/10.1080/19336896.2021.1933872