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Identification and Characterization of the Amphioxus Lck and Its Associated Tyrosine Phosphorylation-Dependent Inhibitory LRR Receptor

Amphioxus (e.g., Branchiostoma belcheri, Bb) has recently emerged as a new model for studying the origin and evolution of vertebrate immunity. Mammalian lymphocyte-specific tyrosine kinase (Lck) plays crucial roles in T cell activation, differentiation and homeostasis, and is reported to phosphoryla...

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Detalles Bibliográficos
Autores principales: Zhou, Jiatao, Xiao, Zhihui, Zhan, Yanli, Qu, Xuemei, Mou, Sisi, Deng, Chong, Zhang, Tianxiang, Lan, Xin, Huang, Shengfeng, Li, Yingqiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8211107/
https://www.ncbi.nlm.nih.gov/pubmed/34149695
http://dx.doi.org/10.3389/fimmu.2021.656366