Sodium alginate microencapsulation improves the short-term oral bioavailability of cannabidiol when administered with deoxycholic acid

BACKGROUND: Cannabidiol (CBD) confers therapeutic effects in some neurological disorders via modulation of inflammatory, oxidative and cell-signalling pathways. However, CBD is lipophilic and highly photooxidative with low oral bioavailability in plasma and brain. In this study, we aimed to design a...

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Detalles Bibliográficos
Autores principales: Majimbi, Maimuna, Brook, Emily, Galettis, Peter, Eden, Edward, Al-Salami, Hani, Mooranian, Armin, Al-Sallami, Hesham, Lam, Virginie, Mamo, John C. L., Takechi, Ryusuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8211198/
https://www.ncbi.nlm.nih.gov/pubmed/34138862
http://dx.doi.org/10.1371/journal.pone.0243858

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8211198/
https://www.ncbi.nlm.nih.gov/pubmed/34138862
http://dx.doi.org/10.1371/journal.pone.0243858

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