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Sodium alginate microencapsulation improves the short-term oral bioavailability of cannabidiol when administered with deoxycholic acid
BACKGROUND: Cannabidiol (CBD) confers therapeutic effects in some neurological disorders via modulation of inflammatory, oxidative and cell-signalling pathways. However, CBD is lipophilic and highly photooxidative with low oral bioavailability in plasma and brain. In this study, we aimed to design a...
Autores principales: | Majimbi, Maimuna, Brook, Emily, Galettis, Peter, Eden, Edward, Al-Salami, Hani, Mooranian, Armin, Al-Sallami, Hesham, Lam, Virginie, Mamo, John C. L., Takechi, Ryusuke |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8211198/ https://www.ncbi.nlm.nih.gov/pubmed/34138862 http://dx.doi.org/10.1371/journal.pone.0243858 |
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