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HSP70-mediated neuroprotection by combined treatment of valproic acid with hypothermia in a rat asphyxial cardiac arrest model

It has been reported that valproic acid (VPA) combined with therapeutic hypothermia can improve survival and neurologic outcomes in a rat asphyxial cardiac arrest model. However, neuroprotective mechanisms of such combined treatment of valproic acid with hypothermia remains unclear. We hypothesized...

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Detalles Bibliográficos
Autores principales: Oh, Joo Suk, Park, Jungtaek, Kim, Kiwook, Jeong, Hyun Ho, Oh, Young Min, Choi, Semin, Choi, Kyoung Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8211226/
https://www.ncbi.nlm.nih.gov/pubmed/34138955
http://dx.doi.org/10.1371/journal.pone.0253328