Signal-regulatory protein alpha is an anti-viral entry factor targeting viruses using endocytic pathways

Signal-regulatory protein alpha (SIRPA) is a well-known inhibitor of phagocytosis when it complexes with CD47 expressed on target cells. Here we show that SIRPA decreased in vitro infection by a number of pathogenic viruses, including New World and Old World arenaviruses, Zika virus, vesicular stoma...

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Detalles Bibliográficos
Autores principales: Sarute, Nicolás, Cheng, Han, Yan, Zhonghao, Salas-Briceno, Karen, Richner, Justin, Rong, Lijun, Ross, Susan R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8211255/
https://www.ncbi.nlm.nih.gov/pubmed/34097709
http://dx.doi.org/10.1371/journal.ppat.1009662

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8211255/
https://www.ncbi.nlm.nih.gov/pubmed/34097709
http://dx.doi.org/10.1371/journal.ppat.1009662

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