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Therapeutic targeting of STAT3 pathways in pancreatic adenocarcinoma: A systematic review of clinical and preclinical literature

BACKGROUND/OBJECTIVES: Pancreatic ductal adenocarcinoma is a highly lethal disease with increasing incidence. Due to high resistance, chemo/radiotherapy has limited success in pancreatic cancer and only marginally prolongs patient survival. Therefore, novel biomarkers and therapeutic targets are nee...

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Detalles Bibliográficos
Autores principales: Peisl, Sarah, Mellenthin, Claudia, Vignot, Lucie, Gonelle-Gispert, Carmen, Bühler, Leo, Egger, Bernhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8211286/
https://www.ncbi.nlm.nih.gov/pubmed/34138876
http://dx.doi.org/10.1371/journal.pone.0252397