Corticosteroid Biosynthesis Revisited: No Direct Hydroxylation of Pregnenolone by Steroid 21-Hydroxylase

Cytochrome P450s (CYPs) are an essential family of enzymes in the human body. They play a crucial role in metabolism, especially in human steroid biosynthesis. Reactions catalyzed by these enzymes are highly stereo- and regio-specific. Lack or severe malfunctions of CYPs can cause severe diseases an...

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Detalles Bibliográficos
Autores principales: Loke, Steffen, Stoll, Anna, Machalz, David, Botrè, Francesco, Wolber, Gerhard, Bureik, Matthias, Parr, Maria Kristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8211424/
https://www.ncbi.nlm.nih.gov/pubmed/34149610
http://dx.doi.org/10.3389/fendo.2021.633785

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8211424/
https://www.ncbi.nlm.nih.gov/pubmed/34149610
http://dx.doi.org/10.3389/fendo.2021.633785

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