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Corticosteroid Biosynthesis Revisited: No Direct Hydroxylation of Pregnenolone by Steroid 21-Hydroxylase
Cytochrome P450s (CYPs) are an essential family of enzymes in the human body. They play a crucial role in metabolism, especially in human steroid biosynthesis. Reactions catalyzed by these enzymes are highly stereo- and regio-specific. Lack or severe malfunctions of CYPs can cause severe diseases an...
Autores principales: | Loke, Steffen, Stoll, Anna, Machalz, David, Botrè, Francesco, Wolber, Gerhard, Bureik, Matthias, Parr, Maria Kristina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8211424/ https://www.ncbi.nlm.nih.gov/pubmed/34149610 http://dx.doi.org/10.3389/fendo.2021.633785 |
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