Attenuated dopamine signaling after aversive learning is restored by ketamine to rescue escape actions

Escaping aversive stimuli is essential for complex organisms, but prolonged exposure to stress leads to maladaptive learning. Stress alters neuronal activity and neuromodulatory signaling in distributed networks, modifying behavior. Here, we describe changes in dopaminergic neuron activity and signa...

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Detalles Bibliográficos
Autores principales: Wu, Mingzheng, Minkowicz, Samuel, Dumrongprechachan, Vasin, Hamilton, Pauline, Xiao, Lei, Kozorovitskiy, Yevgenia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8211450/
https://www.ncbi.nlm.nih.gov/pubmed/33904412
http://dx.doi.org/10.7554/eLife.64041

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8211450/
https://www.ncbi.nlm.nih.gov/pubmed/33904412
http://dx.doi.org/10.7554/eLife.64041

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